Developed comprehensive documentation for the Cannon cluster configuration within the nf-core/configs repository, focusing on guiding users through the use of the -profile cannon option. The work detailed required module loads, provided cluster usage notes, and offered step-by-step instructions for setting up and running pipelines on the Cannon HPC cluster. Using Markdown as the primary language and leveraging strong documentation skills, the contribution aimed to improve reproducibility and streamline onboarding for new users of the Cannon environment. The documentation addressed common setup challenges and clarified operational procedures, supporting both new and experienced users in effectively utilizing the cluster’s resources.