
Developed and delivered a new mutation visualization feature for the cBioPortal/cbioportal-frontend repository, focusing on adding Cancer Cell Fraction and Clonality as selectable axes in the Plots tab. The work involved implementing per-gene ASCN data gating, robust UI logic to handle absent or unsupported data, and improved messaging to guide users through edge cases. Leveraged React and TypeScript to adjust frontend architecture, while utilizing lodash for advanced data processing to preserve zero values and filter invalid entries. Comprehensive unit and end-to-end tests were added to ensure reliability, with all changes integrated into the existing quality assurance and CI workflows.
Month: 2026-04 — Frontend feature delivery and quality improvements for cBioPortal. The primary focus was enhancing mutation visualization and data reliability in cbioportal-frontend. Key features delivered: - Cancer Cell Fraction (CCF) and Clonality visualization added to the Plots tab as new options for plotting mutations, gated on per-gene ASCN data availability. This enables more accurate interpretation of ASCN-derived mutation annotations across genes with sufficient data. Major bugs fixed / robustness improvements: - Implemented gating logic to prevent stale or unsupported selections when ASCN data is absent; the UI now resets to a safe default to maintain valid plots. - Updated data-availability messaging to reflect samples without mutations or clonality as No mutation / Not profiled, reducing user confusion. - Data utility improvements to preserve valid zero values (using numeric checks) and to filter NA clonality values before deduplication, ensuring correct axis data and ordering. Overall impact and accomplishments: - Significantly improved visualization fidelity for ASCN-derived mutations, enabling researchers to compare CCF and clonality alongside cancer type with confidence. - Strengthened data handling and user guidance, reducing edge-case errors in the Plots tab. - Added comprehensive testing coverage and CI-visible validation artifacts to ensure long-term reliability. Technologies / skills demonstrated: - TypeScript, React, and frontend architecture adjustments in PlotsTab.tsx and PlotsTabUtils.tsx. - Advanced data processing with lodash (isNumber, uniq, and filtering) to preserve meaningful values. - Quality assurance through unit tests (PlotsTabUtils.spec.ts) and remote E2E screenshot testing with CI artifacts (MSK 50K, PIK3CA). Delivery detail: - Commit: 5cdceed5c529920dc2b66aae101b0ca5875508d4 (Add Cancer Cell Fraction and Clonality to Plots Tab, #5492).
Month: 2026-04 — Frontend feature delivery and quality improvements for cBioPortal. The primary focus was enhancing mutation visualization and data reliability in cbioportal-frontend. Key features delivered: - Cancer Cell Fraction (CCF) and Clonality visualization added to the Plots tab as new options for plotting mutations, gated on per-gene ASCN data availability. This enables more accurate interpretation of ASCN-derived mutation annotations across genes with sufficient data. Major bugs fixed / robustness improvements: - Implemented gating logic to prevent stale or unsupported selections when ASCN data is absent; the UI now resets to a safe default to maintain valid plots. - Updated data-availability messaging to reflect samples without mutations or clonality as No mutation / Not profiled, reducing user confusion. - Data utility improvements to preserve valid zero values (using numeric checks) and to filter NA clonality values before deduplication, ensuring correct axis data and ordering. Overall impact and accomplishments: - Significantly improved visualization fidelity for ASCN-derived mutations, enabling researchers to compare CCF and clonality alongside cancer type with confidence. - Strengthened data handling and user guidance, reducing edge-case errors in the Plots tab. - Added comprehensive testing coverage and CI-visible validation artifacts to ensure long-term reliability. Technologies / skills demonstrated: - TypeScript, React, and frontend architecture adjustments in PlotsTab.tsx and PlotsTabUtils.tsx. - Advanced data processing with lodash (isNumber, uniq, and filtering) to preserve meaningful values. - Quality assurance through unit tests (PlotsTabUtils.spec.ts) and remote E2E screenshot testing with CI artifacts (MSK 50K, PIK3CA). Delivery detail: - Commit: 5cdceed5c529920dc2b66aae101b0ca5875508d4 (Add Cancer Cell Fraction and Clonality to Plots Tab, #5492).

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