
During April 2025, Hannah Hampson developed an end-to-end kidney single-cell RNA sequencing analysis workflow for the childhealthbiostatscore/CHCO-Code repository. She designed an R Markdown notebook that integrates S3-based data loading, initial quality control, and preprocessing scaffolding, establishing a foundation for scalable and reproducible analysis on the Hyak high-performance computing cluster. Her work included updating the environment to support JAGS, jsonlite, reticulate, boto3, and pandas, enabling cross-language workflows in both R and Python. This setup allows for efficient experimentation and future extension to comparative studies, providing a robust framework for collaborative bioinformatics research and data-driven insights.

Month: 2025-04 — Key outcomes: Delivered an end-to-end Kidney scRNA analysis workflow on Hyak with an initial R Markdown notebook, S3 data loading, QC/preprocessing scaffolding, and a framework for downstream analyses; Updated environment and dependencies to enable JAGS, jsonlite/reticulate, boto3, and pandas; Established reproducible setup for cross-language workflows and HPC-based analyses. This work provides foundation for scalable, reproducible kidney single-cell analysis pipelines on HPC, enabling faster experimentation and broader collaboration. Commit traceability provided via recent commits.
Month: 2025-04 — Key outcomes: Delivered an end-to-end Kidney scRNA analysis workflow on Hyak with an initial R Markdown notebook, S3 data loading, QC/preprocessing scaffolding, and a framework for downstream analyses; Updated environment and dependencies to enable JAGS, jsonlite/reticulate, boto3, and pandas; Established reproducible setup for cross-language workflows and HPC-based analyses. This work provides foundation for scalable, reproducible kidney single-cell analysis pipelines on HPC, enabling faster experimentation and broader collaboration. Commit traceability provided via recent commits.
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