pharmaverse/aNCA
Feb 2025 – Mar 2026
14 Months active
Languages Used
CSSRR MarkdownR ShinyRmdRoxygenShinyCSV
Technical Skills
CSS StylingCode FormattingCode LintingCode MaintenanceCode OrganizationCode Refactoring
Jana Spinner
PROFILE
Jana Spinner
Jana Spinner developed and maintained the pharmaverse/aNCA repository over 14 months, delivering robust pharmacokinetic analysis tools for clinical data workflows. She engineered modular R Shiny applications that streamline noncompartmental analysis, integrating YAML-driven configuration, advanced data mapping, and automated reporting. Her work included refactoring core logic for unit handling, bioavailability calculations, and excretion modeling, while enhancing UI/UX with responsive CSS and dynamic input filtering. Jana prioritized code quality through comprehensive linting, expanded test coverage, and detailed documentation. Leveraging R, JavaScript, and CSS, she improved data integrity, release reliability, and maintainability, enabling reproducible analytics and scalable deployment for clinical research teams.
Overall Statistics
Feature vs Bugs
70%Features
Repository Contributions
1,003Total
Bugs
140
Commits
1,003
Features
329
Lines of code
97,132
Activity Months14
Your Network
21 peopleShared Repositories
21
Angela ManginelliMember
AspridisMember
Bryce C.Member
Gero1999Member
Jana SpinnerMember
jimMember
KobanaMember
LegrasMember
m-kolomanskiMember
Work History
March 2026
20 Commits • 3 Features
Mar 1, 2026March 2026 (Month: 2026-03) focused on delivering robust PK modeling capabilities and an enhanced user experience, while stabilizing the release process. Key technical work centered on bioavailability route logic, YAML-driven unit management for PK calculations, and UI/UX improvements in the Shiny app. The month also included essential maintenance and release housekeeping to ensure reliability and future scalability.
20 Commits • 3 Features
Mar 1, 2026March 2026 (Month: 2026-03) focused on delivering robust PK modeling capabilities and an enhanced user experience, while stabilizing the release process. Key technical work centered on bioavailability route logic, YAML-driven unit management for PK calculations, and UI/UX improvements in the Shiny app. The month also included essential maintenance and release housekeeping to ensure reliability and future scalability.
March 2026
February 2026
57 Commits • 15 Features
Feb 1, 2026February 2026 summary for pharmaverse/aNCA focusing on delivering business value through data integrity improvements, reliability, and release readiness. Key work includes metadata mapping enhancements with WTBL, codebase-wide consistency refinements, major NCA/PKNCA data handling enhancements, and comprehensive settings/template upgrades that enable multi-study configurations. Additionally, quality and packaging improvements (linting, docstrings, tests, and version updates) along with new data support (excretion data) underpin reproducible analyses and faster deployment.
February 2026
57 Commits • 15 Features
Feb 1, 2026February 2026 summary for pharmaverse/aNCA focusing on delivering business value through data integrity improvements, reliability, and release readiness. Key work includes metadata mapping enhancements with WTBL, codebase-wide consistency refinements, major NCA/PKNCA data handling enhancements, and comprehensive settings/template upgrades that enable multi-study configurations. Additionally, quality and packaging improvements (linting, docstrings, tests, and version updates) along with new data support (excretion data) underpin reproducible analyses and faster deployment.
January 2026
129 Commits • 43 Features
Jan 1, 2026January 2026 (pharmaverse/aNCA): Delivered a material upgrade across code quality, unit handling, and configuration management, translating into higher stability, maintainability, and faster feature delivery. Key activities spanned lint fixes, unit-related bug fixes, expanded tests, and documentation improvements, alongside a modernization of settings storage (YAML) and upload handling. The work also included structural refactors (PPTEST in units table, internalized functions), UI/text refinements, and release engineering (version bumps and release notes). Overall this set of changes reduces risk, improves data reliability, and accelerates future development and analytics workflows.
129 Commits • 43 Features
Jan 1, 2026January 2026 (pharmaverse/aNCA): Delivered a material upgrade across code quality, unit handling, and configuration management, translating into higher stability, maintainability, and faster feature delivery. Key activities spanned lint fixes, unit-related bug fixes, expanded tests, and documentation improvements, alongside a modernization of settings storage (YAML) and upload handling. The work also included structural refactors (PPTEST in units table, internalized functions), UI/text refinements, and release engineering (version bumps and release notes). Overall this set of changes reduces risk, improves data reliability, and accelerates future development and analytics workflows.
January 2026
December 2025
111 Commits • 34 Features
Dec 1, 2025December 2025 performance summary for pharmaverse/aNCA: Delivered significant improvements to PPT generation and plotting workflows, enhanced data handling, and strengthened release hygiene. Implemented targeted feature enhancements, bug fixes, and quality improvements that reduce maintenance burden and improve business value of reports and visuals for stakeholders.
December 2025
111 Commits • 34 Features
Dec 1, 2025December 2025 performance summary for pharmaverse/aNCA: Delivered significant improvements to PPT generation and plotting workflows, enhanced data handling, and strengthened release hygiene. Implemented targeted feature enhancements, bug fixes, and quality improvements that reduce maintenance burden and improve business value of reports and visuals for stakeholders.
November 2025
64 Commits • 19 Features
Nov 1, 2025Month: 2025-11 — Pharmaverse/aNCA development sprint focused on delivering high-impact features, stabilizing UI interactions, enhancing plotting capabilities, expanding tests and documentation, and preparing packaging for release. The work emphasizes business value through improved UX, reliable data visualizations, and cleaner release processes.
64 Commits • 19 Features
Nov 1, 2025Month: 2025-11 — Pharmaverse/aNCA development sprint focused on delivering high-impact features, stabilizing UI interactions, enhancing plotting capabilities, expanding tests and documentation, and preparing packaging for release. The work emphasizes business value through improved UX, reliable data visualizations, and cleaner release processes.
November 2025
October 2025
28 Commits • 8 Features
Oct 1, 2025Month 2025-10: Delivered UI improvements, architecture refinements, and release discipline across pharmaverse/aNCA, driving user experience, reliability, and faster release cycles. Key outcomes include targeted UI/UX enhancements, safer processing flows, and stronger test/CI practices that reduce risk and maintenance burden while enabling scalable growth. Key features delivered: - Loading popup UI improvements: added close button and ensured the popup can be closed; refactor to close on error (commits 884c80028b7ecc4c9f7a429844be857bf1976e6e and 7d9cff3e68efa0c8d8e55b3f1974cf19ae40e035) - Units handling refactor: simplify units using local options to reduce global dependencies (commit 59a1fe5a262be8a0cf0884dd1f74ac0b4a95ad6c) - Remove modal refactor: move remove modal outside of resnca for better isolation and maintainability (commit 77a22439c6c1de387c2df930ccfea3399260483f) - Data tab UI: disable Next button during processing to prevent duplicate actions (commit f92a51c2917a59ab80d1c0b6fadf4508b1b06e15) - Test warnings and lint cleanup: suppress test warnings, lint updates to improve reliability (commits 34486fbf87ea2439493d86abb39f5c98742cc395, 000fb25b51bf3bf396e72c361296873016c8a484, eb7fa186bc6086f787c1a4fc2b579d02ff7f1cda) - Version and package maintenance: bump package version across repo (commits 156f01f7bf4e80f9d8c4ccdfb968c64106396109, 8e2d2e4518d5872711df5c5e55bdcab237c08fe4, fdc6b7ec53c226b90b8747faf39c51a16ae67095) - Test tooling and dependencies management: updates to test dependencies and setup scripts (commits 2e7a884c8e277bb90c214cc5f714958a7722bc0c, 56dcbd511a736b172f67c943f7d4fa753c2996bf, ca431456e40ed99655f6ab579be3721946e4696e, cf88cb3dc3a037d8aea5d5afeae3668dbc282cee) - CI, linting and workflow configuration updates: YAML/workflow refinements for new dependencies and coverage; cyclocomp additions (commits 74c9e532e00c21086e8358dd522266c6b96f8eb0, 863ab54588e718fa291ed49efed7d76833efff02, da78beef68fbbb4fc55222fa27b3362d503fb0ac, 72691e70791249bb0df6096a82f3d75f3cec3fc7, a808bbd404dd047e3c8016527df8a4afd5e0fb07, f934823bd33774d3fbc5a82e941e32e8de461804, b1d6013bd2aa4428fdfcb3180c0cb32f4ac85cf0) Major bugs fixed: - Lint/config fixes: address missing roxygen2 and devtools in extra packages and tilde usage corrections; update RoxygenNote (commits 4dfeaaec9d15b5e6783eeda1dc0740815b2b3cdd, 8ada9f9471fbf306df1dd4ea61167574bd206615, e25d7f9b239a99856b603f7b4fff1482ddab630d) - Version bumps and packaging metadata updates: align version metadata across releases (commits ba85f8d44783696487667f9a4d1afe5394ae9d2d, b40f663a1ecabe446154f3c15d8d363742634cd7, aee1813778f325480b4f9b6ba49d96c04ed777ee) Overall impact and accomplishments: - Strengthened UX with responsive loading indicators, safer processing paths, and clearer modular boundaries, reducing user confusion and error states. - Improved code quality and maintainability through local option patterns, modal isolation, and consistent versioning. - Reduced risk in production by disabling duplicate actions, suppressing flaky test warnings, and tightening CI/test configurations, enabling faster and more reliable releases. - Enabled scalable growth with better separation of concerns and a robust release process through continuous integration and tooling updates. Technologies/skills demonstrated: - UI/UX design and React-like patterns (loading popup, modal handling) - Architectural refactoring (local options for units, modal isolation) - Quality engineering (linting, test suppression, CI/CD workflow tuning) - Release engineering (version bumps, packaging metadata alignment, dependency management)
October 2025
28 Commits • 8 Features
Oct 1, 2025Month 2025-10: Delivered UI improvements, architecture refinements, and release discipline across pharmaverse/aNCA, driving user experience, reliability, and faster release cycles. Key outcomes include targeted UI/UX enhancements, safer processing flows, and stronger test/CI practices that reduce risk and maintenance burden while enabling scalable growth. Key features delivered: - Loading popup UI improvements: added close button and ensured the popup can be closed; refactor to close on error (commits 884c80028b7ecc4c9f7a429844be857bf1976e6e and 7d9cff3e68efa0c8d8e55b3f1974cf19ae40e035) - Units handling refactor: simplify units using local options to reduce global dependencies (commit 59a1fe5a262be8a0cf0884dd1f74ac0b4a95ad6c) - Remove modal refactor: move remove modal outside of resnca for better isolation and maintainability (commit 77a22439c6c1de387c2df930ccfea3399260483f) - Data tab UI: disable Next button during processing to prevent duplicate actions (commit f92a51c2917a59ab80d1c0b6fadf4508b1b06e15) - Test warnings and lint cleanup: suppress test warnings, lint updates to improve reliability (commits 34486fbf87ea2439493d86abb39f5c98742cc395, 000fb25b51bf3bf396e72c361296873016c8a484, eb7fa186bc6086f787c1a4fc2b579d02ff7f1cda) - Version and package maintenance: bump package version across repo (commits 156f01f7bf4e80f9d8c4ccdfb968c64106396109, 8e2d2e4518d5872711df5c5e55bdcab237c08fe4, fdc6b7ec53c226b90b8747faf39c51a16ae67095) - Test tooling and dependencies management: updates to test dependencies and setup scripts (commits 2e7a884c8e277bb90c214cc5f714958a7722bc0c, 56dcbd511a736b172f67c943f7d4fa753c2996bf, ca431456e40ed99655f6ab579be3721946e4696e, cf88cb3dc3a037d8aea5d5afeae3668dbc282cee) - CI, linting and workflow configuration updates: YAML/workflow refinements for new dependencies and coverage; cyclocomp additions (commits 74c9e532e00c21086e8358dd522266c6b96f8eb0, 863ab54588e718fa291ed49efed7d76833efff02, da78beef68fbbb4fc55222fa27b3362d503fb0ac, 72691e70791249bb0df6096a82f3d75f3cec3fc7, a808bbd404dd047e3c8016527df8a4afd5e0fb07, f934823bd33774d3fbc5a82e941e32e8de461804, b1d6013bd2aa4428fdfcb3180c0cb32f4ac85cf0) Major bugs fixed: - Lint/config fixes: address missing roxygen2 and devtools in extra packages and tilde usage corrections; update RoxygenNote (commits 4dfeaaec9d15b5e6783eeda1dc0740815b2b3cdd, 8ada9f9471fbf306df1dd4ea61167574bd206615, e25d7f9b239a99856b603f7b4fff1482ddab630d) - Version bumps and packaging metadata updates: align version metadata across releases (commits ba85f8d44783696487667f9a4d1afe5394ae9d2d, b40f663a1ecabe446154f3c15d8d363742634cd7, aee1813778f325480b4f9b6ba49d96c04ed777ee) Overall impact and accomplishments: - Strengthened UX with responsive loading indicators, safer processing paths, and clearer modular boundaries, reducing user confusion and error states. - Improved code quality and maintainability through local option patterns, modal isolation, and consistent versioning. - Reduced risk in production by disabling duplicate actions, suppressing flaky test warnings, and tightening CI/test configurations, enabling faster and more reliable releases. - Enabled scalable growth with better separation of concerns and a robust release process through continuous integration and tooling updates. Technologies/skills demonstrated: - UI/UX design and React-like patterns (loading popup, modal handling) - Architectural refactoring (local options for units, modal isolation) - Quality engineering (linting, test suppression, CI/CD workflow tuning) - Release engineering (version bumps, packaging metadata alignment, dependency management)
September 2025
33 Commits • 16 Features
Sep 1, 2025September 2025 — pharmaverse/aNCA: Implemented unit updates, UI and data-filtering refinements, enhanced excretion analysis, and testing/quality improvements to strengthen data accuracy, reporting reliability, and release readiness for NCA analyses.
33 Commits • 16 Features
Sep 1, 2025September 2025 — pharmaverse/aNCA: Implemented unit updates, UI and data-filtering refinements, enhanced excretion analysis, and testing/quality improvements to strengthen data accuracy, reporting reliability, and release readiness for NCA analyses.
September 2025
August 2025
55 Commits • 10 Features
Aug 1, 2025In August 2025, pharmaverse/aNCA delivered a focused set of stability, modularity, and capability improvements. Release discipline was strengthened via package version bumps across multiple commits to align release versions. UX and clarity were improved by renaming visualization to Exploration and aligning function names to explore, and by label/document updates. Modularity and maintainability advanced with a new parameter plots module and relocation of boxplots to NCA results. The detect_study_types workflow was enhanced with tests, improved inputs/outputs, IV bolus/Infusion distinction, and metadata/document updates. Support for tau mapping was added as an optional feature. Multiple lint and quality improvements were completed, and the user guide was updated to reflect changes.
August 2025
55 Commits • 10 Features
Aug 1, 2025In August 2025, pharmaverse/aNCA delivered a focused set of stability, modularity, and capability improvements. Release discipline was strengthened via package version bumps across multiple commits to align release versions. UX and clarity were improved by renaming visualization to Exploration and aligning function names to explore, and by label/document updates. Modularity and maintainability advanced with a new parameter plots module and relocation of boxplots to NCA results. The detect_study_types workflow was enhanced with tests, improved inputs/outputs, IV bolus/Infusion distinction, and metadata/document updates. Support for tau mapping was added as an optional feature. Multiple lint and quality improvements were completed, and the user guide was updated to reflect changes.
July 2025
88 Commits • 35 Features
Jul 1, 2025July 2025 monthly summary for pharmaverse/aNCA highlighting key delivered features, major bug fixes, business impact, and skills demonstrated. Focused on robustness of ratio computations, plotting UX, data mapping reliability, and release readiness.
88 Commits • 35 Features
Jul 1, 2025July 2025 monthly summary for pharmaverse/aNCA highlighting key delivered features, major bug fixes, business impact, and skills demonstrated. Focused on robustness of ratio computations, plotting UX, data mapping reliability, and release readiness.
July 2025
June 2025
86 Commits • 34 Features
Jun 1, 2025June 2025 performance highlights for pharmaverse/aNCA: Stabilized critical data workflows and expanded modeling capabilities across logslope, dosing, excretion, and reporting. Delivered core features and bug fixes with a strong focus on data integrity, maintainability, and packaging. Notable outcomes include: profile naming refactor (dosno to profile), volume conversions refactor with new data paths, AmountU column integration, groundwork and refinements for excretion tables and related conversions, API export enhancements, and comprehensive tests and documentation improvements. Major bug fixes addressed key reliability gaps in data input, parameter verification, and UI behavior (e.g., logslope imputation bug with required settings fields; DOSEU conversion removal; no-flag and verify-params issues; trailing s removal). These changes reduce incorrect dosing computations and improve consistency across reports and exports.
June 2025
86 Commits • 34 Features
Jun 1, 2025June 2025 performance highlights for pharmaverse/aNCA: Stabilized critical data workflows and expanded modeling capabilities across logslope, dosing, excretion, and reporting. Delivered core features and bug fixes with a strong focus on data integrity, maintainability, and packaging. Notable outcomes include: profile naming refactor (dosno to profile), volume conversions refactor with new data paths, AmountU column integration, groundwork and refinements for excretion tables and related conversions, API export enhancements, and comprehensive tests and documentation improvements. Major bug fixes addressed key reliability gaps in data input, parameter verification, and UI behavior (e.g., logslope imputation bug with required settings fields; DOSEU conversion removal; no-flag and verify-params issues; trailing s removal). These changes reduce incorrect dosing computations and improve consistency across reports and exports.
May 2025
56 Commits • 28 Features
May 1, 2025In May 2025, delivered substantive features and stability improvements for pharmaverse/aNCA, focusing on readiness of NCAProfile, data processing enhancements, and maintainability. Completed DOSNOA/NCAPROFILE migration with tolerance/impute updates and testing setup, introduced dosing data filtering, fixed critical interval and slope bugs, and strengthened testing and lint practices. These changes reduce data processing risk, improve analytics accuracy, and accelerate future releases.
56 Commits • 28 Features
May 1, 2025In May 2025, delivered substantive features and stability improvements for pharmaverse/aNCA, focusing on readiness of NCAProfile, data processing enhancements, and maintainability. Completed DOSNOA/NCAPROFILE migration with tolerance/impute updates and testing setup, introduced dosing data filtering, fixed critical interval and slope bugs, and strengthened testing and lint practices. These changes reduce data processing risk, improve analytics accuracy, and accelerate future releases.
May 2025
April 2025
113 Commits • 38 Features
Apr 1, 2025April 2025 (pharmaverse/aNCA) delivered meaningful enhancements and stability improvements across refactoring, testing, and data handling to strengthen reliability of NCA computations and ease future maintenance. Highlights include refactoring matrix ratio calculations to use nominal time, extensive documentation and test improvements, targeted bug fixes across PKNCA integration, AUC/interval logic, and result handling, plus feature work on DOSNOA, bioavailability checks, and enhanced parameter selection UX. These changes collectively reduce risk in production, improve data integrity, and accelerate release readiness while showcasing strong proficiency in code quality, data modeling, and domain-specific calculations.
April 2025
113 Commits • 38 Features
Apr 1, 2025April 2025 (pharmaverse/aNCA) delivered meaningful enhancements and stability improvements across refactoring, testing, and data handling to strengthen reliability of NCA computations and ease future maintenance. Highlights include refactoring matrix ratio calculations to use nominal time, extensive documentation and test improvements, targeted bug fixes across PKNCA integration, AUC/interval logic, and result handling, plus feature work on DOSNOA, bioavailability checks, and enhanced parameter selection UX. These changes collectively reduce risk in production, improve data integrity, and accelerate release readiness while showcasing strong proficiency in code quality, data modeling, and domain-specific calculations.
March 2025
82 Commits • 19 Features
Mar 1, 2025March 2025 monthly summary for pharmaverse/aNCA: Delivered comprehensive ADNCA naming/refactor, advanced PK/NGCA data handling with semi-dynamic intervals, and integration of bioavailability across results and descriptive statistics. Strengthened code quality, documentation, and test coverage, with stability improvements in calculations and plotting to reduce regressions and improve decision-grade PK metrics. Business value delivered through clearer APIs, more accurate pharmacokinetic metrics, and faster, more maintainable development cycles.
82 Commits • 19 Features
Mar 1, 2025March 2025 monthly summary for pharmaverse/aNCA: Delivered comprehensive ADNCA naming/refactor, advanced PK/NGCA data handling with semi-dynamic intervals, and integration of bioavailability across results and descriptive statistics. Strengthened code quality, documentation, and test coverage, with stability improvements in calculations and plotting to reduce regressions and improve decision-grade PK metrics. Business value delivered through clearer APIs, more accurate pharmacokinetic metrics, and faster, more maintainable development cycles.
March 2025
February 2025
81 Commits • 27 Features
Feb 1, 2025February 2025 focused on delivering a robust ratio analytics capability, stabilizing data handling, and laying groundwork for a cleaner, more maintainable codebase in pharmaverse/aNCA. Implemented a comprehensive ratioCalculations module with single and multiple ratio functions, added BPP ratio support, and created a dedicated module for all ratio utilities to streamline downstream analytics. UI improvements included text size adjustments for lambda plots, and consolidation of ratios into a single tab for improved UX; additional UI enhancements like download buttons for the ratios table were implemented. Fixed critical bugs affecting data integrity and user workflows, including IX value handling, removal of jsonlite from the click path, check fail handling, parameter filter in results, predose duplicates, metabolite data issues, and edge-case handling for half-life calculations. Strengthened quality and release readiness through lint cleanups, docstrings, updated tests, documentation updates, and package version bumps.
February 2025
81 Commits • 27 Features
Feb 1, 2025February 2025 focused on delivering a robust ratio analytics capability, stabilizing data handling, and laying groundwork for a cleaner, more maintainable codebase in pharmaverse/aNCA. Implemented a comprehensive ratioCalculations module with single and multiple ratio functions, added BPP ratio support, and created a dedicated module for all ratio utilities to streamline downstream analytics. UI improvements included text size adjustments for lambda plots, and consolidation of ratios into a single tab for improved UX; additional UI enhancements like download buttons for the ratios table were implemented. Fixed critical bugs affecting data integrity and user workflows, including IX value handling, removal of jsonlite from the click path, check fail handling, parameter filter in results, predose duplicates, metabolite data issues, and edge-case handling for half-life calculations. Strengthened quality and release readiness through lint cleanups, docstrings, updated tests, documentation updates, and package version bumps.
Activity
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Quality Metrics
Correctness91.4%
Maintainability91.4%
Architecture88.6%
Performance86.4%
AI Usage20.8%
Skills & Technologies
Programming Languages
CSSCSVHTMLJavaScriptMarkdownPythonRR MarkdownR ShinyRmd
Technical Skills
Backend DevelopmentBioavailability CalculationBug FixBug FixingBuild Process ManagementCDISC StandardsCI/CDCSSCSS StylingClinical Data AnalysisClinical Data ManagementCode CleanupCode FormattingCode LintingCode Maintenance
Repositories Contributed To
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