
Farhad Khajoueinejad contributed to the broadinstitute/warp repository by developing and refining bioinformatics pipelines for large-scale genomics. He upgraded the Opossum Pipeline’s indexing from TBI to CSI, enabling support for large chromosomes and improving cross-pipeline compatibility. Using Python, Bash, and WDL, Farhad fixed a critical join barcode step, enhancing reliability for large genomic datasets. He also integrated MitoFinder into the BuildIndices workflow, adding optional mitochondrial data processing and annotation. Additionally, he optimized the snm3C demultiplexing workflow by refining read thresholds, which improved data quality and resource efficiency. His work emphasized maintainability, documentation, and reproducibility across workflows.

October 2025: Implemented optional mitochondrial data support in the BuildIndices WDL for broadinstitute/warp by integrating MitoFinder, enabling optional appending of mitochondrial sequences and annotations. Added dedicated tasks for mitochondrial annotation and GTF merging, updated pipeline versions and changelogs, and prepared the workflow to process mitochondrial data end-to-end.
October 2025: Implemented optional mitochondrial data support in the BuildIndices WDL for broadinstitute/warp by integrating MitoFinder, enabling optional appending of mitochondrial sequences and annotations. Added dedicated tasks for mitochondrial annotation and GTF merging, updated pipeline versions and changelogs, and prepared the workflow to process mitochondrial data end-to-end.
Monthly summary for 2025-08 (broadinstitute/warp): Focused on quality improvement and reproducibility of the snm3C demultiplexing workflow. Delivered a targeted feature refinement that reduces the read threshold to better match typical sample loads, and updated the pipeline version and changelog to ensure traceability. No major bugs fixed this month. Impact: higher-quality demultiplexed data, reduced compute/resource usage, and faster, more reliable downstream analyses. Technologies demonstrated: WDL pipeline tuning, versioning and changelog practices, commit traceability, and cross-team collaboration.
Monthly summary for 2025-08 (broadinstitute/warp): Focused on quality improvement and reproducibility of the snm3C demultiplexing workflow. Delivered a targeted feature refinement that reduces the read threshold to better match typical sample loads, and updated the pipeline version and changelog to ensure traceability. No major bugs fixed this month. Impact: higher-quality demultiplexed data, reduced compute/resource usage, and faster, more reliable downstream analyses. Technologies demonstrated: WDL pipeline tuning, versioning and changelog practices, commit traceability, and cross-team collaboration.
November 2024 focused on stabilizing and scaling the Opossum Pipeline in broadinstitute/warp. Delivered indexing upgrade from TBI to CSI to support large-chromosome data and updated pipeline versions and changelogs across related pipelines. Fixed a critical join barcode step issue, improving reliability when processing large genomic datasets and ensuring cross-pipeline compatibility. Coordinated with multiple repos to align versions and documentation, reducing downstream maintenance.
November 2024 focused on stabilizing and scaling the Opossum Pipeline in broadinstitute/warp. Delivered indexing upgrade from TBI to CSI to support large-chromosome data and updated pipeline versions and changelogs across related pipelines. Fixed a critical join barcode step issue, improving reliability when processing large genomic datasets and ensuring cross-pipeline compatibility. Coordinated with multiple repos to align versions and documentation, reducing downstream maintenance.
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