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Michael Harper

PROFILE

Michael Harper

Developed and delivered an end-to-end UBAM processing and kinetics removal pipeline for the populationgenomics/production-pipelines repository, enabling automated handling of PacBio ubam files sourced from Google Cloud Storage. Leveraging Python scripting and command line tools such as samtools, the solution removed kinetic data and outputted cleaned BAM files to a specified directory. The work included robust file handling, standardized output naming, and path corrections to streamline downstream data processing and reduce manual intervention. By focusing on reproducibility and clarity, the pipeline improved data quality and facilitated smoother integration with subsequent bioinformatics analytics, enhancing overall pipeline stability and usability.

Overall Statistics

Feature vs Bugs

100%Features

Repository Contributions

5Total
Bugs
0
Commits
5
Features
1
Lines of code
72
Activity Months1

Work History

November 2025

5 Commits • 1 Features

Nov 1, 2025

Month 2025-11 — Major feature delivered for populationgenomics/production-pipelines. Implemented the UBAM processing and kinetics removal pipeline enabling end-to-end handling of PacBio ubam files from Google Cloud Storage, removal of kinetic data via samtools, and saving cleaned BAMs to a defined output directory. Standardized output naming and path handling to improve downstream usability and clarity (changing extensions to .bam and naming conventions like '_no_kinetics_bam'). This work enhances data quality, reproducibility, and pipeline stability, reducing manual intervention and enabling smoother integration with downstream analytics.

Activity

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Quality Metrics

Correctness100.0%
Maintainability96.0%
Architecture96.0%
Performance96.0%
AI Usage20.0%

Skills & Technologies

Programming Languages

Python

Technical Skills

Python scriptingbioinformaticscloud computingcommand line toolsdata processingfile handlingscripting

Repositories Contributed To

1 repo

Overview of all repositories you've contributed to across your timeline

populationgenomics/production-pipelines

Nov 2025 Nov 2025
1 Month active

Languages Used

Python

Technical Skills

Python scriptingbioinformaticscloud computingcommand line toolsdata processingfile handling