2025-12 Monthly Summary: Two high-impact deliverables across Bioconda and Galaxy Tools IUC, focused on stability, scalability, and researcher value. Key features delivered include a Build System and Dependency Upgrade for omark (0.4.1) with uv-build as a host dependency to improve compatibility and build reliability, and the introduction of FastOMA, a scalable orthology inference tool with multi-genome support and comprehensive reporting. Major bugs fixed include resolving omark build issues flagged in #61106 via the upgrade and dependency changes. Overall impact: more reliable builds, expanded capabilities for large-scale genomics analyses, and a stronger, thoroughly tested toolchain. Technologies demonstrated: package management and host-dependency resolution, Galaxy tool packaging and shed configuration, test automation, linting improvements, and memory tuning for Nextflow.