
Yejin Choi refactored and enhanced the single-cell RNA sequencing analysis workflow in the childhealthbiostatscore/CHCO-Code repository, focusing on improving pseudotime analysis and enabling cohort-specific data subsetting. Using R and Python, Yejin updated environment paths to ensure reproducibility and introduced new R Markdown files to support data exploration and reporting. The technical approach emphasized modular code structure and reproducible research practices, allowing for more granular cohort insights and streamlined downstream validation. This work deepened the analytical capabilities of the workflow, addressed the need for flexible cohort analysis, and produced reporting-ready artifacts for collaborative bioinformatics research and validation.

Month: 2025-09 1) Key features delivered: Refactor and enhance single-cell RNA sequencing analysis workflow in CHCO-Code, including pseudotime improvements and cohort-specific data subsetting; update Python environment paths; add new R Markdown files for data exploration and analysis. 2) Major bugs fixed: None reported this month. 3) Overall impact and accomplishments: Improved analysis reproducibility and efficiency; enabled more granular cohort insights; prepared reporting-ready artifacts for downstream validation and collaboration. 4) Technologies/skills demonstrated: R, Python environment management, pseudotime analysis, data subsetting, R Markdown, and Git version control.
Month: 2025-09 1) Key features delivered: Refactor and enhance single-cell RNA sequencing analysis workflow in CHCO-Code, including pseudotime improvements and cohort-specific data subsetting; update Python environment paths; add new R Markdown files for data exploration and analysis. 2) Major bugs fixed: None reported this month. 3) Overall impact and accomplishments: Improved analysis reproducibility and efficiency; enabled more granular cohort insights; prepared reporting-ready artifacts for downstream validation and collaboration. 4) Technologies/skills demonstrated: R, Python environment management, pseudotime analysis, data subsetting, R Markdown, and Git version control.
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