In May 2025, delivered critical robustness and configurability improvements to FindTransferAnchors in satijalab/seurat. Fixed the SCT normalization handling bug to correctly select SCT models and ensure proper assay data usage when reference and query datasets have differing normalization statuses. Removed an unsupported check for mixing SCT and non-SCT assays, reducing edge-case failures. Extended FindTransferAnchors to support references with multiple SCT models, enabling more complex reference configurations and broader test coverage for diverse SCT setups. These changes enhance cross-dataset integration reliability, improve user workflows, and support more flexible SCT-based analyses across projects.

February 2025 monthly summary for satijalab/seurat focusing on business value and technical achievements. The key delivery this month was a robust improvement to image plotting naming and collision handling. Specifically, the image plotting naming separator was changed from underscore to tilde (~) to reliably join image names with boundary identifiers, and a safeguard was added to prevent the tilde from being used in FOV names to avoid collisions. This reduces ambiguity in generated image identifiers, prevents potential conflicts in downstream analyses, and improves overall reliability of visualization workflows.